Probiotic 50
Probiotic 50
Probiotic 50
Probiotic 50
High-performance probiotic for active individuals
Probiotic 50 is a highly potent, shelf-stable, dairy-free probiotic that delivers 50 billion CFUs from 10 clinically researched commensal strains per capsule. DFS Probiotic 50 delivers more than 2.5x the CFUs per serving of other sports nutrition probiotics.+Designed to support serious training and performance goals, Probiotic 50 promotes gut health, immune function, and athletic recovery.* It helps maintain a balanced microbiome, a healthy inflammatory response, and supports nutrient absorption — key for endurance, strength, and overall performance.* Probiotic 50 may also help relieve occasional GI complaints common in athletes.* Whether training hard or competing, this probiotic helps athletes stay resilient from the inside out.*
+Based on CFU count per serving compared to Thorne FloraSport 20B and Klean Probotic 15B as of October 2025.
| SHELF STABLE FORMULA | VEGAN | STRAIN TRANSPARENCY | TRAVEL-FRIENDLY |
PBM050-DS
Recommended Use : As a dietary supplement, take 1 capsule per day with a meal, at any time of day, or as directed by your health care practitioner.
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High-performance probiotic for active individuals
Probiotic 50 is a highly potent, shelf-stable, dairy-free probiotic that delivers 50 billion CFUs from 10 clinically researched commensal strains per capsule. DFS Probiotic 50 delivers more than 2.5x the CFUs per serving of other sports nutrition probiotics.+Designed to support serious training and performance goals, Probiotic 50 promotes gut health, immune function, and athletic recovery.* It helps maintain a balanced microbiome, a healthy inflammatory response, and supports nutrient absorption — key for endurance, strength, and overall performance.* Probiotic 50 may also help relieve occasional GI complaints common in athletes.* Whether training hard or competing, this probiotic helps athletes stay resilient from the inside out.*
+Based on CFU count per serving compared to Thorne FloraSport 20B and Klean Probotic 15B as of October 2025.
| SHELF STABLE FORMULA | VEGAN | STRAIN TRANSPARENCY | TRAVEL-FRIENDLY |
PBM050-DS
ZERO GRAMS OF SUGAR
EXERCISE RECOVERY
JOINT HEALTH*
VASCULAR SUPPORT*
TESTED FOR BANNED SUBSTANCES
NON-GMO
ZERO GRAMS OF SUGAR
EXERCISE RECOVERY
JOINT HEALTH*
VASCULAR SUPPORT*
TESTED FOR BANNED SUBSTANCES
NON-GMO
The next evolution in performance nutrition is here. Support the intersection of gut health and athletic recovery with a performance-grade probiotic crafted to help athletes stay locked in and in a rhythm*
Consists of 10 of the most highly researched probiotic strains, with each strain and specific CFU count being fully disclosed
The DESigns for sport® difference
- 50 billion CFUs of broad-spectrum probiotic strains
- Full transparency on identity and CFU count of each strain
- Travel-friendly, shelf-stable with no refrigeration necessary
- Superior tolerance and resistance to stomach acid and bile salts
- Delayed-release technology for optimal survivability in the lower GI tract
- State-of-the-art moisture-, oxygen-, and light-resistant, desiccant-lined packaging: Keeps potency intact, extends shelf life, no refrigeration needed
- Gluten-free, dairy-free, soy-free, non-GMO, and vegan
- NFS Certified for Sport®
Performance Nutrition for All Who Train
Performance Nutrition for All Who Train
Helps to power athletic performance, starting in the gut*
Helps promote healthy post-exercise inflammatory responses through a healthy, balanced microbiome*
Helps with relief from occasional bloating and GI complaints common in athletes or those on strict diets*
Supports a healthy immune response in athletes*
May help support healthy gut-brain axis signaling, which may promote mental resilience and emotional well-being*
Supports nutrient absorption (e.g., amino acids, minerals)*
answers to all your questions
What are Probiotics?
Probiotics are live and active microorganisms that support health and may help provide health benefits when consumed at a high enough level.
Probiotics offer many supposed benefits, including but not limited to:
- Supporting digestion and food breakdown*
- Maintaining a healthy gut microbiome*
- Improving gut balance and health*
- Supporting immunity*
What’s the Difference Between a Prebiotic and a Probiotic?
While probiotics are live microorganisms, prebiotics are food for probiotics – in the form of non-digestible fiber – that provides the fuel for probiotics and/or additional microbes.
When is The Best Time to Take Probiotics?
There are two common times of day that is most beneficial when taking probiotics: during the beginning of the day, or before going to bed. Ideally, probiotics should be taken on an empty stomach to ensure its benefits are optimized.
What makes Probiotic 50 different from regular probiotics?
The 10 strains in Probiotic 50 are specifically selected for athletic applications—supporting recovery, reducing inflammation markers, and improving nutrient absorption. It's NSF Certified for Sport, shelf-stable, and uses delayed-release technology so bacteria survive stomach acid.
What are CFUs in Probiotics?
CFUs stand for colony-forming units, and is a quantitative measurement of the amount of live microorganisms in a probiotic drink, food item, or supplement. For daily support, aim for between 1-10 billion CFUs.
Does probiotic 50 need to be refrigerated?
Probiotic 50 is shelf-stable and no refrigeration required given its state-of-the-art moisture-, oxygen-, and light-resistant, desiccant-lined packaging to protect probiotics and extend shelf life to fit travel and day-to-day needs.
Product Research Sheet Video
Product Research Sheet
Power Your Performance from the Inside Out
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Key Performance Benefits
- Helps power athletic performance, starting in the gut
- Supports healthy post-exercise inflammatory responses through a healthy, balanced microbiome
- Helps restore microbial balance after athletic training, travel, or occasional exercise-related stress
- Helps reduce occasional bloating and GI complaints common in athletes or those on strict diets
- Supports a healthy immune response in athletes
- May help support healthy gut-brain axis signaling, which may promote mental resilience and emotional well-being
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What This Product Is
Probiotic 50 is formulated to deliver 50 billion colony-forming units (CFUs) from 10 highly researched commensal probiotic strains per capsule. It combines clinically backed probiotic strains to support serious training and performance goals for athletes.
This high-performance probiotic formula is positioned to support gut health, immune function, athletic recovery, a balanced microbiome, healthy inflammatory response, and nutrient absorption. For athletes training hard or competing, Probiotic 50 is designed to support resilience from the inside out.
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Ingredient and Formula Highlights
- 50 billion CFUs of broad-spectrum probiotic strains at clinically significant amounts
- Fully discloses the identity and specific CFU count of each strain
- Shelf-stable and no refrigeration required to fit travel and day-to-day needs
- Superior tolerance and resistance to stomach acid and bile salts
- Delayed-release capsules designed for survivability through stomach acid and release in the lower GI tract
- Moisture-, oxygen-, and light-resistant desiccant-lined packaging to protect probiotics and extend shelf life
- Gluten-free, dairy-free, soy-free; non-GMO
- Vegetarian and vegan
- NSF Certified for Sport
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Mechanism of Action
Gut Health and Athletic Performance
Exercise places stress on the gastrointestinal tract, especially during endurance sports and higher-volume training. Probiotic support may help athletes maintain GI comfort, microbial balance, and training consistency.
Immune and Recovery Support
The International Society of Sports Nutrition supports probiotics as a health-supporting supplement for athletes due to their potential to support immune status, nutrient status, recovery following muscle-damaging exercise, and gut health.
Microbiome, Inflammation, and Resilience
Clinically researched probiotic strains may help support a healthy inflammatory response, upper respiratory tract health, mood, nutrient absorption, and resilience under physical stress.
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Athletic Applications
- Endurance athletes
- Strength and power athletes
- Athletes under travel or competition stress
- Individuals with occasional GI complaints during training
- Athletes seeking gut, immune, and recovery support
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Researched Strains
Bifidobacterium longum (Bl-05)
A short-chain fatty acid–producing bacterium relevant to gut microbial diversity and endurance support.
Bifidobacterium animalis lactis (HN019)
A researched strain associated with beneficial gut microbes and immune readiness.
Bifidobacterium breve (Bbr8)
A strain studied for gut integrity and support during GI stress.
Bifidobacterium bifidum (UABc-10)
A strain associated with digestive support and nutrient status.
Lactobacillus plantarum (UALp-05)
A clinically relevant strain positioned to support a healthy inflammatory response.
Lactobacillus acidophilus (La-14)
A widely used strain associated with immune activity and athletic resilience.
Lactobacillus rhamnosus (GG)
A strain studied for occasional GI complaints in athletes.
Lactobacillus paracasei (UALpc-04)
A strain relevant to digestive comfort and nutrient absorption.
Lactobacillus casei (UALc-03)
A strain associated with mucosal immune support following intense exercise.
Lactobacillus salivarius (Ls-33)
A strain that may support oral microbiome balance, an area relevant to nitric oxide physiology and performance.
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Suggested Use
Take 1 capsule per day with a meal or as directed by your healthcare practitioner.
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Why is a probiotic relevant for athletes?
Exercise, travel, dietary shifts, and high training loads can place stress on the gut and immune system. Probiotic support may help athletes maintain microbial balance, GI comfort, recovery, and resilience.
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Does Probiotic 50 need refrigeration?
No. The formula is shelf-stable and designed for travel and day-to-day use.
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What makes this formula athlete-oriented?
It delivers 50 billion CFUs from 10 researched strains, uses delayed-release capsule technology, and is NSF Certified for Sport.
This information is intended for use by physicians and other licensed healthcare practitioners as a basis for determining whether to recommend this product to their patients.
Why NSF Certified for Sport®?
We align ourselves with NSF as a testament to our commitment towards industry safety standards. Determined to become the leading supplement and education resource in the performance nutrition category, our alliance with NSF further reinforces our commitment to product excellence.*
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