In short: They’re the same thing. The terms are often used interchangeably in the supplement industry.

Magnesium bisglycinate is well-known for its calming properties, making it a popular choice for those looking to support relaxation and restful sleep. While it’s not a sedative, some individuals may feel more relaxed or slightly drowsy after taking it—especially if taken in the evening or when the body is deficient in magnesium. For that reason, many people prefer to take it at night.

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It’s well-tolerated, less likely to cause laxative effects, and has superior bioavailability compared to forms like magnesium oxide or citrate.

There are many supposed benefits of magnesium bisglycinate, including but not limited to:

• Stress support
• Improved digestion
• Heart and cardiovascular health support
• Sleep and relaxation support
• Bone mineralization support
• Muscle recovery

Magnesium bisglycinate is a supplement that contains both magnesium and glycine. Magnesium bisglycinate contains two glycine molecules to each of the magnesium molecules, and has been shown to support stress responses, healthy digestion, muscle recovery, sleep, and more.

Magnesium bisglycinate is generally well-tolerated and considered one of the gentlest forms of magnesium, especially on the digestive system. Most people don’t experience side effects, but as with any supplement, individual responses may vary.

In some cases, especially at higher doses, magnesium can cause:

• Mild digestive upset
• Loose stools (though this is less common with bisglycinate compared to other forms like citrate or oxide)
• A sense of relaxation or drowsiness, which is why many prefer to take it in the evening